DeMar DeRozan had 25 points, Kyle Lowry added 23 points and nine assists, and the Raptors beat the Nets 104-99 on Tuesday night.
Brook Lopez had 35 points, one shy of his season high, for the Nets, who lost the season series to the Raptors for the first time since 2009-10.
The Raptors rallied from a 16-point halftime deficit to get back on track at home after their franchise-record, 12-game home win streak ended Sunday against Houston.
Toronto's 58-42 halftime hole equaled its biggest of the season, done in a loss at Golden State in November.
The Raptors got within two courtesy of a 22-9 run over the final 5:55 of the third quarter and finally jumped in front on Patrick Patterson's 3-pointer to open the fourth.