The exhibit will allow the museum the chance to reveal its complete holdings of the artist's work -- some 150 pieces -- which have never before been seen in their entirety.
"The Actor," a work accidentally damaged at the museum, has been restored and will be included. The exhibit opens April 27.
The works going on display will range in date from a self-portrait composed in 1900 when Picasso was only 19-years-old to the Standing Nude and Seated Musketeer the Spaniard created in 1968 when he was 87, ArtKnowledgeNews reports.
"The Metropolitan's collection reflects the full breadth of Picasso's multi-sided genius as it asserted itself over the course of his long and influential career," said the magazine.
Auction powerhouses Sotheby's and Christie's will offer two rare Picassos not seen on the market in decades.
Christie's "Nude, Green Leaves and Bust" is estimated to bring $70 million to $90 million May 4. Sotheby's "Femme au Chapeau, Buste" that belonged to a sister of President John Kennedy will be sold May 5. It's estimated to sell for $8 million to $12 million.