Mantle Cell Glossary

Nodular Mantle Cell Lymphoma
Diffuse MCL
Blastic MCL
Beta-2 Microglobulin
Lactate Dehydrogenase (LDH)
Graft-Versus-Host-Disease (GVHD)

Nodular mantle cell lymphoma: a type of MCL where the malignant cells are distributed within "nodules," which are spherical structures inside the lymph glands.

Diffuse MCL: a type of MCL in which the malignant cells are distributed in a diffuse fashion within the lymph gland. This type of MCL invades the lymph gland without arranging itself into nodules.

Blastic MCL: This refers to a type of MCL that contains immature-looking cells that resemble cells known as a blasts.

Beta-2 microglobulin: A portion of a molecule that is found on nearly all cells. Elevated levels can indicate the presence of certain diseases.

Lactate Dehydrogenase (LDH): An enzyme detected in the blood. In lymphoma, an increase in LDH levels sometimes correlates with the presence and/or increase of tumor cells.

Graft-versus-host-disease (GVHD): A serious complication of allogeneic stem cell transplantation that occurs when the donor’s immune cells attack the patient’s normal tissue.
 

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