Shots were fired outside the W Hotel in Times Square early Saturday, damaging the facade, police said.
Chicago rapper Keith Cozart, better known as Chief Keef, was in the vicinity of the hotel when the shots were fired, but it wasn't clear if he was the intended target, police sources said.
No one was injured in the shooting, the NYPD said.
The gunshot was reported shortly before 5 a.m. on 47th Street between Seventh and Eighth avenues, police said. Two men, ages 29 and 30, told police they were standing outside when they heart a shot.
Two men fled immediately after the shot went off, police said. They haven't been found.
No one has been arrested.
The investigation is ongoing.