She filed her petition Tuesday in Los Angeles, citing irreconcilable differences.
The couple got married in 1989 and have a son together.
The 50-year-old Helgenberger plays Catherine Willows on CBS' highly rated drama, "CSI: Crime Scene Investigation." She won a best supporting actress Emmy in 1990 for the series "China Beach."
The 58-year-old Rosenberg was a regular on the TV series "LA Law" and "The Guardian," and received an Emmy nomination for a guest role on "ER." He is the current present of SAG, which remains embroiled in contract negotiations with Hollywood producers over a new contract for actors.
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