Leo, who lives in Stone Ride in Ulster County, will co-star with Academy Award nominee Jesse Eisenberg in a movie to be filmed in the mid-Hudson Valley, according to The Times Herald-Record of Middletown.
The head of the Hudson Valley Film Commission tells the newspaper that the film "Predisposed'' was written by Philip Dorling of Woodstock and Ron Nyswaner of Stone Ridge.
Nyswaner will also direct the film, a comedy about a college-bound teen who attempts to drug his rehab-seeking mother so health insurance will pay for treatments.
Leo won the Oscar Sunday night for Best Supporting Actress for her role in "The Fighter.''
Eisenberg was nominated for Best Actor for his role in "The Social Network.''